The army post in Biloxi Blues is not in Mississippi. The film was actually filmed at Fort Chaffee, near Fort Smith, Arkansas. Van Buren, across the Arkansas River from Fort Smith, stood in for downtown Biloxi.
Biloxi Blues is the second part of playwright Neil Simon's semi-autobiographical theater trilogy about his growth from adolescence into adulthood. Directed by Mike Nichols and starring Broadway star Matthew Broderick as Eugene Jerome, the story follows him from the nest of Brooklyn to army basic training in Biloxi, Mississippi, where he gets his introduction to the world beyond Coney Island.