What to know
Established in 1880, Argenta Drug Co. is the oldest continuously operating pharmacy west of the Mississippi River. Located in the Argenta Arts District, Argenta Drug is housed in the oldest brick building in North Little Rock. Until 2006, a vintage classic Coca-Cola ad was painted on the 4th Street side of the building, but has since been restored. When you step in to the drugstore, you step back in time. Little has changed since the 1950s, as it sports vintage apothecary wallpaper, the original pressed tin ceiling and hand-laid tile flooring.