Hamburg is located in Ashley County, about 125 miles from Little Rock. The town was created in 1849, two months after Ashley County was formed from part of Drew County. 

The downtown square, with its gazebo, now serves as home-base to the annual Armadillo Festival, held the first weekend in May since 1970. A few blocks surrounding this square known as the Hamburg Commercial Historic District is on the National Register of Historic Places as are several other structures in town such as the Watson House, now the Ashley County Museum

Among Hamburg's famous former residents are writer Charles Portis, author of such novels as True Grit, and former NBA star Scottie Pippen.